Basic Research

Basic Research - KAR & MTC Campus

S. No. Title Principal Investigator Funding Agency Duration
1Effect of maternal diabetes during pregnancy on placental epigenetics and its association with retinal development and risk of retinopathy in infantsWellcome Trust India Alliance early career fellowship2024-2029Dr. Aatish Mahajan
2Impact of Urban Air Pollution on ocular surface microbiome changes and its effect on dry eye disease Indian Council of Medical Research 2021-2024Dr Arunasri Kotakonda
3 Setting up pathogen surveillance systems beyond SARS-CoV2 Rockefeller Foundation2022-2024Dr Bhupesh Bagga
4 Role of TRP ion channels in regulating corneal endothelial response to increased intraocular pressure Science and Engineering Research Board2023-2026Dr Charanya Ramachandran
5Silk Fibroin carrier for the culture and transplantation of corneal endotheliumDepartment of Biotechnology 2024-2027 Dr Charanya Rmachandran
6Identification of diagnostic biomarkers in vitreous/ aqueous fluid of ocular tuberculosis patients.Indian Council of Medical Research 2023-2026 Dr Himanshu Behera
7Investigating a crystiInvestigating a-crystallin-particulate matter interactions to assess the impact of air pollution on ocular protein homeostasis Indian Council of Medical Research 2023-2026 Dr Inderjeet Kaur
8Development of intraocular implant providing controlled and localized combination drug therapy- towards efficacious treatment of diabetic retinopathyIndian Council of Medical Research 2024-2027Dr Inderjeet Kaur
9Understanding the role of RD3 gene in retinal development and disease Science and Engineering Research Board2022-2025Dr Indumathi Mariappan
10Generation and evaluation of universal donor stem cells for applications in allogenic cell therapy for retinal dystrophic conditions Indian Council of Medical Research 2022-2025 Dr Indumathi Mariappan
11Immunomodulation as an adjuctive therapy for the treatment in fungal endophthalmitis Indian Council of Medical Research 2022-2025Dr Joveeta Joseph
12 Clinical utility of Extracellular Vesicles as a miRNA delivery carrier for the treatment of Mutidrug Resistant EndophthalmitisIndian Council of Medical Research 2024-2027 Dr Joveeta Joseph
13 Proof of Concept" study of effects of Plazomicin on Islotes from Bacterial Keratitis and /or ConjuctivitisCIPLA 2023-2026 Dr Joveeta Joseph
14JCB/2023/000033 -J C BoseScience and Engineering Research Board20232028Dr Mohammad Javed Ali
15Role of TET family proteins in Retinoblastoma Indian Council of Medical Research 2023-2026Dr Mamatha Reddy
16New therapeutic approach for corneal dystrophy via CRISPR mediated SLC4A11 gene correction in an in-vitro and in-vivo system using advanced cRGD decorated lipo-polymeric nanoplexesScience and Engineering Research Board 2024-2027Dr Muralidhara Ramappa
17Project management system/tool (IRMI)India Research Management InitiativeWellcome Trust India Alliance2024-2025 Ms Neelima Sharma
18Efficacy of SEED’s novel anti-myopia contact lens (daily disposable) in controlling myopia progression – Randomized Controlled Clinical Trial SEED2021-2024 Dr Pavan K. Verkicharla
19An Evaulation of the effectivness of contact lenses utilising S.T.O.P technology in slowing dowm myopia progression STOP 2022-2024Dr Pavan K. Verkicharla
20Ophthalmic Carl Camras Translational Research PFIZER2024-2025Dr Prem Nandhini Satgunam
21 Baby Vision Screener (BaViS): A device to screen visual cognitive milestones in early childhoodIndian Council of Medical Research 2024-2026Dr PremNandhini Satgunam
22 Development of Automated Gaze Detection of Babies to study Visual Cognition Department of Biotechnology 2024-2027 Dr Prem Nandhini Satgunam
23 Artificial Intelligence enabled referral pathways for early diagnosis of complications arising from diabetes: application to diabetic retinopathyIndian Council of Medical Research 2023-2026Dr Padmaja K Rani
24Biological and molecular understanding of chemotherapy resistance and metastasis in Retinoblastoma Ramalingaswami re entry Fellowship 2023-2026Dr Pallavi Rani
25Therapeutic and immunomodulatoryeffects of human limbus-derivedmesenchymal stem cells in a rat model ofallergic conjunctivitis Indian Council of Medical Research 2023-2026Dr Pragnya Rao
26 CRC : Centre for Health Outcomes Research and Economics (IHOPE)Wellcome Trust India Alliance2020-2025Dr Raja Narayanan
27CRTP : Centre for Health Outcomes Research and Economics (IHOPE) Wellcome Trust India Alliance2020-2025Dr Raja Narayanan
28Exploring potential interplay of tear cytokine levels and confocal biomicroscopy in progressive keratoconus for better clinical diagnosis-SRGScience and Engineering Research Board2024-2026Dr Rashmi Deshmukh
29 Cell-based therapy for lacrimal gland regeneration and repair in a preclinical animal model of aqueous deficiency dry eye disease Wellcome Trust India Alliance-Early Career2023-2028 Dr Swati Singh
30rom infection to autoimmunity in an immune privileged organ: a case study in tuberculosis of the eye DBT India Alliance - Intermediate Fellowship 2019-2024Dr Soumyava Basu
31Preclinical development of long acting subconjuncyival steriod sparing agent to treat posterior uveitisIndian Council of Medical Research 2023-2026Dr Soumyava Basu
32Understanding the role of gasdermin D in the pathogenesis of mucormycosis-CRG Science and Engineering Research Board2023-2026Dr Sanhita Roy
33Rational design and structure-function analysis of antimicrobial peptides tailored to treat fungal ocular infections Velux Stiftung Foundation-Switerland 2023-2026Dr Sanhita Roy
34 Adult Mesenchymal stem cells as adjuctive therapy for bacterial keratitis: A novel approach to treat corneal infections Indian Council of Medical Research 2022-2025Dr Sachin Shukla
35Vision loss, disability, and multimorbidity among the elderly population in Telangana, India - The Longitudinal Eye Health Aging and Disability Study (LEADS)"Wellcome Trust India Alliance2023-2028Dr Srinivas Marmamula
36 Exploring variation in humans ability to free -fuse targets for cyclopean visual experience DST- Cognitive Science Research Initiative 2023-2026Dr Shrikant Bharadwaj
37Tensor-based Machine Learning for Early Detection of Keratoconus AI4ICPS2024-2026Dr Shrikant Bhadrawaj
38Understanding optical and neural limitations to visual performance in keratoconus Fulbright-Nehru Fellowships2023-2025Dr Shrikant Bharadwaj
39Harnessing polymicrobial interactions to tackle antimicrobial resistance: an ex-vivo study in human cornea model Science and Engineering Research Board2022-2024Dr Sanchita Mitra
40 Biomimetic hydrogel for the treatment of blinding corneal diseasesSREE PVF2022-2025Dr Sayan Basu
41 Improving Corneal Healing Via Modulation of Tissues Ulverscroft Foundation2020-2025Dr Sayan Basu
42Corneal Characterization under biaxial loading in physiological conditions-CRGScience and Engineering Research Board2023-2026Dr Sayan Basu
43" A device based on digital photo elasticity for in-vivo characterization of corneal birefringence Department of Biotechnology 2024-2027Dr Sayan Basu ( Co PI )
44 Elucidating the molecular mechanisms and biomarkers associated with progression and prognosis of retinoblastoma-CRGScience and Engineering Research Board2022-2025Dr Swathi Kaliki
45 Investigating the potential cross talk between mitochondrial and nuclear gene in primary open angle glaucomaIndian Council of Medical Research 2023-2026Dr Subhabrata Chakrabarti
46Therapeutic potential of decellularized cornea matrix (DCM) hydrogel for corneal scars and stromal replacement in trauma conditions: Pre-clinical studyIndian Council of Medical Research 2022-2025Dr Vivek Singh
47Biomimetic hydrogel for the treatment of blinding corneal diseases SREE PVF2022-2025Dr Sayan Basu
48 Preclinical and phase 0/1 clinical investigation of minimally invasive microneedle patch for effective chemotherapy in Retinoblastoma Indian Council of Medical Research 2023-2026Dr Vishal R Raval
49Subretinal Fluid in Coats’ Disease: Biochemical composition and association of lipid-laden macrophages with inflammatory biomarkers Jack McGovern Coats' Disease Foundation 2024-2025Dr Vishal Raval
50Phase I/II Multicenter Randomized Controlled Clinical Trial of Mesenchymal Stem Cell Therapy for Severe Ocular Surface Chemical injury - University of Illinois- ChicagoUniversity of Illinois - Chicago2022-2024Dr Sayan Basu