Visual Functions Laboratory

Visual Functions lab

Visual acuity (VA), the most measured outcome variable in randomized clinical trials to test the efficacy of drugs is a poor marker of the disease severity has large test-retest variability and reflects only the central 1o of the retinal function. Therefore, the overall objective is to quantify and understand the role of functional biomarkers in early detection and management strategies of retinal diseases and play a key role in preventing loss of vision. The lab will primarily focus on evaluating advanced retinal function tests (colour vision, spatial and temporal contrast sensitivity, dark adaptometry and microperimetry) and designing novel retinal function tests that can act as a functional marker for early detection, quantify the severity of the disease, evaluate treatment outcomes, and provide insight into prognostic outcomes.

The aims of the visual functions lab are as follows:

  1. To develop retinal functional markers that will aid in early detection of retinal diseases and in management of retinal diseases over the treatment course
  2. Integrate retinal functions with structural and imaging technology to holistically evaluate structure-function relationship that will lead to better understanding of the disease process
  3. The lab will also focus on designing and innovate test paradigms that can potentially lead to development of occupation-centric colour vision tests that determine their real-world ability to perform in a particular working environment. In addition, the research in the lab will also invest in testing and determining the most optimal chromatic filter that maximizes visual performance in individuals with CVD in their day-to-day activities.

Ongoing Research projects

  1. Residual visual function assessments in patients post retinal detachment surgeries
  2. Efficacy of treatment outcomes in Diabetic retinopathy
  3. Understanding the disease pathogenesis of BRVO using novel functional markers
  4. Assessment of efficacy of colour vision aids on visual search tasks

List of publications - https://scholar.google.ca/citations?user=IKfjoFUAAAAJ&hl=en

Lab members

Principal Investigator

Dr Amithavikram R Hathibelagal

Research Optometrists:

Suchana Shirodkar

Past:

  1. Diwaakar Karthikeyan
  2. Sargam Dhingra


List of PGD projects mentored (2018-present)

  1. Anil Yadav - Project title: Normative database for rod and cone flicker sensitivity
  2. Manoj K Manoharan* - Project title: Flicker sensitivity in myopes
  3. Gayatri Yadav - Project title: Assessment of visual functions in patients before and after antiVEGF in patients with wet AMD
  4. Yasmeen Mulani - Project title: Visual functions in patients with recovered endophtalmitis
  5. Ramya N - Project title: Colour vision assessment in patients with pediatric optic neuritis
  6. Om Prakash Yadav - Project title: VEP assessment in myopes
  7. Monika Thakur - Project title: Custom pupillary device for measuring melanopsin response
  8. Sanma Baidya - Project title: Effect of antiVEGF on OCTA in patients with wet AMD
  9. Sumaiya Aftab
  10. Shyam Sundar - Project title: Retrospective analysis of patients with geographic atrophy
  11. Anushka Sain
  12. Farhat Yasmine - Project title: Retrospective analysis of patients with Stargardts disease correlating vision with signs
  13. Vishal Prajapati
  14. Indrani Jayagopi - Project title: Normative database for ON and OFF pathways using a tablet-based test
  15. Helna Babu
  16. Mrutunjoy Das
  17. Phuntsok Tshering - Project title: Tablet based ON and OFF pathway to distinguish rod and cone-dominated diseases
  18. Manali Sikder*
  19. Haseeb Syed* - Project title: Assessment of colour vision and pupil longitudinally in patients with optic neuritis - A case series
  20. Rinki Gupta - Project title: Flicker sensitivity in young children
  21. Sowmiya Sri
  22. Meghana Megi - Project title: Intrasession repeatability of flicker thresholds in patients with Stargardt’s disease
  23. Aryan Thapa - Project title: Assessment of ON and OFF Pathways in patients with rod-dominated diseases – using psychophysics and electroretinography
  24. Diksha Chachada
  25. Dileep - Project title: Comparison of flicker thresholds with microperimetry findings in patients in cone-dominated diseases
  26. MD Yasin - Project title: Comparison of ERG parameters obtained using a hand-held device amongst patients with inherited retinal diseases (IRD) - A retrospective study
    *jointly-mentored